This fact sheet is for the video Understanding the Nuclear Pore: Gatekeeper of the Nucleus.
The nuclear pore facilitates the transport of materials between the nucleus and cytosol, resolving the challenge posed by the nuclear envelope in maintaining the nucleus environment. Each pore, composed of 456 proteins known as nucleoporins, features a complex structure with membrane ring, scaffold, and channel nucleoporins, along with cytosolic fibrils and a nuclear basket. Small molecules pass through rapidly, while larger molecules require active transport using nuclear signals and receptors, powered by GTP.
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